Prebiotic oligosaccharides change the concentrations of short-chain fatty acids and the microbial population of mouse bowel
Open Access
- 27 March 2009
- journal article
- Published by Zhejiang University Press in Journal of Zhejiang University-SCIENCE B
- Vol. 10 (4), 258-263
- https://doi.org/10.1631/jzus.b0820261
Abstract
The purpose of this study was to clarify effects of selected oligosaccharides on concentrations of cecal short-chain fatty acids (SCFAs), total large bowel wet weight and wall weight, and cecal microbiota levels in mice. Mice were respectively given gavage of selected fructooligosaccharides (FOS), galactooligosaccharides (GOS), mannanoligosaccharides (MOS), and chitooligosaccharides (COS) [1000 mg/(kg body weight·d)]. Control group was given physiological saline solution. After 14 d treatment, SCFAs and lactate in mice cecum were significantly increased (P<0.05) by intake of oligosaccharides, especially FOS and GOS. Thus, providing these oligosaccharides as ingredients in nutritional formulas may benefit the gastrointestinal tract.Keywords
This publication has 20 references indexed in Scilit:
- A probiotic treatment containing Lactobacillus, Bifidobacterium and Enterococcus improves IBS symptoms in an open label trialJournal of Zhejiang University-SCIENCE B, 2006
- Prebiotic Galactooligosaccharides Reduce Adherence of EnteropathogenicEscherichia colito Tissue Culture CellsInfection and Immunity, 2006
- Effects of the dietary supplementation with fructooligosaccharides on the excretion of nitrogen and phosphorus inMiichthys miiuyfriesJournal of Zhejiang University SCIENCE, 2005
- Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning?Gut, 2002
- Lactobacillus‐ and bifidobacterium‐mediated antigenotoxicity in the colon of ratsNutrition and Cancer, 1996
- Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirusThe Lancet, 1994
- Regulatory effects of bifidobacteria on the growth of other colonic bacteriaJournal of Applied Bacteriology, 1994
- Effects of short chain fatty acids on gut morphology and function.Gut, 1994
- Effect of fructo‐oligosaccharides on intestinal microfloraMolecular Nutrition & Food Research, 1987
- Influence of chronic lactulose ingestion on the colonic metabolism of lactulose in man (an in vivo study).JCI Insight, 1985