Measurement of body water by multifrequency bioelectrical impedance spectroscopy in a multiethnic pediatric population
Open Access
- 1 November 1999
- journal article
- research article
- Published by Elsevier BV in The American Journal of Clinical Nutrition
- Vol. 70 (5), 847-853
- https://doi.org/10.1093/ajcn/70.5.847
Abstract
Background: Bioelectrical impedance spectroscopy (BIS) may provide a noninvasive, rapid method for the assessment of total body water (TBW), extracellular water (ECW), and intracellular water (ICW). Few studies, however, have examined the accuracy of BIS in pediatric populations. Objective: Our objective was to evaluate the accuracy of BIS for the measurement of TBW, ECW, and ICW in healthy children. Design: Dual-energy X-ray absorptiometry (DXA), total body potassium (TBK), and BIS measurements were performed in 347 children (202 males and 145 females aged 4–18 y). The reference values for TBW, ECW, and ICW were defined by using a DXA+TBK model. BIS values were evaluated by using the method of Bland and Altman. A randomly selected calibration group (n = 231) was used to derive new BIS constants that were tested in the remaining group (n = 116). Results: BIS values were highly correlated with the reference values (r2 = 0.94–0.97, P < 0.0001), but differences between the BIS and DXA+TBK models for individuals were significant (P < 0.001). Use of new BIS constants reduced the mean differences between the BIS and DXA+TBK models; the SDs of the mean differences were improved (1.8 L for TBW, 1.4 L for ICW, and 1.0 L for ECW) for the total population. Conclusions: On a population basis, BIS can be calibrated to replace the DXA+TBK model for the assessment of TBW, ECW, and ICW in healthy children. The accuracy of the BIS measurement in individual children may be refined further by using age- and sex-specific adjustments for the BIS calibration constants.Keywords
This publication has 14 references indexed in Scilit:
- Potential errors in the application of mixture theory to multifrequency bioelectrical impedance analysisPhysiological Measurement, 1998
- Bioimpedance spectroscopy technique: intra-, extracellular, and total body waterMedicine & Science in Sports & Exercise, 1997
- Predicting body cell mass with bioimpedance by using theoretical methods: a technological reviewJournal of Applied Physiology, 1997
- Asymmetry of the total body water prediction bias using the impedance indexNutrition, 1997
- Deuterium and Bromide Dilution, and Bioimpedance Spectrometry Independently Show That Growth Hormone-Deficient Adults Have an Enlarged Extracellular Water Compartment Related to Intracellular WaterJournal of Clinical Endocrinology & Metabolism, 1997
- Multifrequency bioelectric impedance measurements for predicting body water compartments in duchenne muscular dystrophyNeuromuscular Disorders, 1996
- Comparison of extra-cellular fluid volume measurement in children by99Tcm-DPTA clearance and multi-frequency impedance techniquesPhysiological Measurement, 1994
- The five-level model: a new approach to organizing body-composition researchThe American Journal of Clinical Nutrition, 1992
- STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENTThe Lancet, 1986
- Measurement of body fat and hydration of the fat-free body in health and diseaseMetabolism, 1985