Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells.
Open Access
- 1 February 1989
- journal article
- research article
- Published by Informa UK Limited in Molecular and Cellular Biology
- Vol. 9 (2), 851-853
- https://doi.org/10.1128/mcb.9.2.851
Abstract
Only a few of the genes involved in DNA repair in mammalian cells have been isolated, and induction of a DNA repair gene in response to DNA damage has not yet been established. DNA polymerase beta (beta-polymerase) appears to have a synthetic role in DNA repair after certain types of DNA damage. Here we show that the level of beta-polymerase mRNA is increased in CHO cells after treatment with several DNA-damaging agents.Keywords
This publication has 26 references indexed in Scilit:
- Induction of yeast DNA ligase genes in exponential and stationary phase cultures in response to DNA damaging agentsCurrent Genetics, 1986
- Improved conditions for activity gel analysis of DNA polymerase catalytic polypeptidesAnalytical Biochemistry, 1983
- Identification of DNA polymerases involved in DNA excision repair in diploid human fibroblasts.Journal of Biological Chemistry, 1983
- Recombination of parent and daughter strand DNA after UV-irradiation in mammalian cellsNature, 1983
- Structure of repaired sites in human DNA synthesized in the presence of inhibitors of DNA polymerases alpha and beta in human fibroblastsBiochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1983
- Excision repair and DNA synthesis with a combination of HeLa DNA polymerase beta and DNase V.Journal of Biological Chemistry, 1983
- The roles of DNA polymerases alpha, beta, and gamma in DNA repair synthesis induced in hamster and human cells by different DNA damaging agents.Journal of Biological Chemistry, 1982
- Reactions of calf thymus DNA polymerases α and β with native DNA damaged by thymine starvation or by methyl methanesulphonate treatment ofEscherichia colicellsFEBS Letters, 1981
- Reactivity of KB cell deoxyribonucleic acid polymerases .alpha. and .beta. with nicked and gapped deoxyribonucleic acidBiochemistry, 1980
- Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells: I. The effect on HeLa and Chinese hamster cell survival of alkylation of cellular macromoleculesChemico-Biological Interactions, 1971