Hepatocellular Carcinoma with Inferior Vena Cava and Right Atrium Tumor Thrombus
Open Access
- 29 July 2021
- journal article
- Published by Vilnius University Press in Acta medica Lituanica
- Vol. 28 (2), 10
- https://doi.org/10.15388/amed.2021.28.2.10
Abstract
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer and cancer related deaths worldwide. Metastasis of HCC into the cardiac cavity is mostly caused by direct tumor thrombus invasion through the major hepatic veins and of vena cava inferior with continuous extension into the right cardiac cavity. Right heart metastasis without invasion of inferior vena cava (IVC), which may be caused by haematogenous spread of cancer cells, is rarely reported. We report a case of HCC with IVC and right atrium (RA) thrombus in a patient who presented to us with decompensated cardiac failure. Strikingly, the patient was young and with negative serum HBsAg, and anti-HCV results. Our case highlights a rare presentation of metastatic intracardiac tumor thrombus involving the RA in advanced HCC without any symptoms of cardiac failure, and henceforth, the role of screening echocardiography for all patients with advanced HCC especially with vena caval involvement to rule out intracardiac thrombus.Keywords
This publication has 12 references indexed in Scilit:
- Hepatocellular carcinoma on cirrhosis complicated with tumoral thrombi extended to the right atrium: results in three cases treated with major hepatectomy and thrombectomy under hypothermic cardiocirculatory arrest and literature reviewWorld Journal of Surgical Oncology, 2016
- Survival Benefit of Surgical Treatment for Hepatocellular Carcinoma with Inferior Vena Cava/Right Atrium Tumor Thrombus: Results of a Retrospective Cohort StudyAnnals of Surgical Oncology, 2012
- Hepatocellular carcinoma with right atrial tumor thrombus: Report of a caseSurgery Today, 2011
- The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biologyThe Esophagus, 2009
- Hepatocellular Carcinoma With Intracavitary Cardiac Involvement: A Case Report and Review of the LiteratureThe American Journal of Cardiology, 2008
- Preoperative predictors of vascular invasion in hepatocellular carcinomaEuropean Journal of Surgical Oncology, 2008
- Sorafenib in Advanced Hepatocellular CarcinomaThe New England Journal of Medicine, 2008
- Alcohol and hepatocellular carcinomaGastroenterology, 2004
- Sudden death from massive pulmonary tumor embolism due to hepatocellular carcinomaForensic Science International, 2000
- Growth of Hepatocellular Carcinoma into the Right AtriumAnnals of Internal Medicine, 1983