Reassortment of Pandemic H1N1/2009 Influenza A Virus in Swine
- 18 June 2010
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 328 (5985), 1529
- https://doi.org/10.1126/science.1189132
Abstract
The emergence of pandemic H1N1/2009 influenza demonstrated that pandemic viruses could be generated in swine. Subsequent reintroduction of H1N1/2009 to swine has occurred in multiple countries. Through systematic surveillance of influenza viruses in swine from a Hong Kong abattoir, we characterize a reassortant progeny of H1N1/2009 with swine viruses. Swine experimentally infected with this reassortant developed mild illness and transmitted infection to contact animals. Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted.Keywords
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