Intraindividual comparison of epithelial defects during laser in situ keratomileusis using standard and zero-compression Hansatome microkeratome heads
- 1 January 2004
- journal article
- clinical trial
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Cataract & Refractive Surgery
- Vol. 30 (1), 123-126
- https://doi.org/10.1016/s0886-3350(03)00657-6
Abstract
Purpose: To determine the difference between the standard and a modified (zero-compression) Hansatome® microkeratome head (Bausch & Lomb) in the incidence of epithelial defects. Setting: Department of Ophthalmology, Johann Wolfgang Goethe-University, Frankfurt am Main, Germany. Methods: Ninety-three patients (186 eyes) with a mean age of 39.1 years ± 9.5 (SD) having laser in situ keratomileusis (LASIK) in both eyes were enrolled in a prospective randomized study using intraindividual comparison. In 1 eye, the flaps were created with the Hansatome microkeratome using the standard Hansatome head and in the other eye, the flaps were created with a microkeratome head with a modified design (zero-compression head). Intraoperative evaluation of epithelial defects was done using a standardized protocol. Statistical evaluation was performed with McNemar and Bowker tests. Results: Epithelial defects occurred in 21 eyes (22.6%) in which the standard head was used and in 2 eyes (2.1%) in which the zero-compression head was used. In the former group, 15 (16.1%) of the epithelial defects were larger than 1.5 mm2; the remaining 6 (6.4%) were smaller than 1.5 mm2. In the latter group, both epithelial defects were smaller than 1.5 mm2; both patients also had an epithelial defect in the eye in which the standard Hansatome head was used. The difference between the 2 Hansatome heads in the incidence (P<.001, McNemar) and size (P<.001, Bowker) of the epithelial defects was statistically significant. Conclusions: The Hansatome microkeratome with a zero-compression head significantly reduced the occurrence of intraoperative epithelial defects. The change in the construction of the Hansatome head is a useful improvement in LASIK technology.Keywords
This publication has 10 references indexed in Scilit:
- Risk factors for epithelial erosions in laser in situ keratomileusisJournal of Cataract & Refractive Surgery, 2002
- Risk factors for intraoperative epithelial defect in laser in-situ keratomileusisAmerican Journal of Ophthalmology, 2002
- Decreased incidence of epithelial defects during laser in situ keratomileusis using intraoperative nonpreserved carboxymethylcellulose sodium 0.5% solutionJournal of Cataract & Refractive Surgery, 2002
- The Wound Healing Response After Laser In Situ Keratomileusis and Photorefractive KeratectomyAmerican Journal of Ophthalmology, 2001
- Intact corneal epithelium is essential for the prevention of stromal haze after laser assisted in situ keratomileusisBritish Journal of Ophthalmology, 2001
- Sloughing of corneal epithelium and wound healing complications associated with laser in situ keratomileusis in patients with epithelial basement membrane dystrophyAmerican Journal of Ophthalmology, 2000
- Diffuse lamellar keratitis associated with epithelial defects after laser in situ keratomileusisJournal of Cataract & Refractive Surgery, 2000
- Corneal Haze Development After PRK Is Regulated by Volume of Stromal Tissue RemovalCornea, 1998
- A Test for Symmetry in Contingency TablesJournal of the American Statistical Association, 1948
- Note on the sampling error of the difference between correlated proportions or percentagesPsychometrika, 1947