Influence of Dietary Protein on Motor Fluctuations in Parkinson's Disease
- 1 March 1987
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 44 (3), 270-272
- https://doi.org/10.1001/archneur.1987.00520150026014
Abstract
• On a nearly zero protein diet, 11 patients with Parkinson's disease with the "on-off" effect demonstrated great sensitivity to levodopa (L-dopa)-carbidopa and reduced fluctuations. Eight patients required a 41% reduction in total L-dopa dosage and discontinuation of all adjuvant therapy to reduce the preponderance of chorea. On a high-protein diet, all patients were immobilized by bradykinesia for most of the day. A low-protein dietary regimen during the daytime offers an important technique for the control of fluctuations in patients with Parkinson's disease who are receiving L-dopa-carbidopa.Keywords
This publication has 2 references indexed in Scilit:
- RATIONALE FOR EARLY USE OF LEVODOPA IN PARKINSONISMThe Lancet, 1986
- SYNTHETIC AMINO ACIDS AND THE NATURE OF l‐DOPA TRANSPORT AT THE BLOOD‐BRAIN BARRIERJournal of Neurochemistry, 1975