Fast forward genetics based on virus-induced gene silencing
- 1 April 1999
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Plant Biology
- Vol. 2 (2), 109-113
- https://doi.org/10.1016/s1369-5266(99)80022-3
Abstract
Gene expression in plants can be suppressed in a sequencespecific manner by infection with virus vectors carrying fragments of host genes. Recent developments have revealed that the mechanism of this gene silencing is based on an RNA-mediated defence against viruses. It has also emerged that a related mechanism is involved in the post-transcriptional silencing that accounts for between line variation in transgene expression and cosuppresion of transgenes and endogenous genes. The technology of virus-induced gene silencing is being refined and adapted as a high throughput procedure for functional genomics in plants.Keywords
This publication has 1 reference indexed in Scilit:
- Initiation and Maintenance of Virus-Induced Gene SilencingPlant Cell, 1998