Oophorectomy in Premenopausal Women
- 1 February 2007
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Obstetrics & Gynecology
- Vol. 109 (2, Part 1), 347-354
- https://doi.org/10.1097/01.aog.0000252700.03133.8b
Abstract
To compare health-related quality-of-life outcomes and sexual functioning among premenopausal women who underwent bilateral salpingo-oophorectomy (BSO) versus ovarian conservation at the time of hysterectomy. This is a secondary data analysis of premenopausal women who underwent hysterectomy for benign gynecologic disease in the Medicine or Surgery and the Total or Supracervical Hysterectomy randomized trials. Bilateral salpingo-oophorectomy was performed at the patients' requests or to treat intraoperative ovarian pathology. Health-related quality-of-life outcomes and sexual functioning were assessed using the Medical Outcomes Study SF-36, Sexual Problems Scales, and several other measures at 4 weeks, 6 months, and 2 years after hysterectomy. Mean age at hysterectomy was higher for the 49 women who underwent BSO compared with the 112 women with ovarian conservation (45 versus 40, P<.001). At 6 months, the BSO group demonstrated less improvement than women with ovarian conservation on scales for body image (2 versus 14, P=.01), sleep problems (4 versus 16, P<.01), and the SF-36 Mental Component Summary (4 versus 10, P=.03). There were no differences in any measure of sexual functioning between the groups. Hot flushes, urinary incontinence, and pelvic pain were similar in both groups. At 2-year follow-up, all measures of health-related quality-of-life and sexual functioning appeared similar by BSO status. Women who underwent BSO had less improvement in some aspects of health-related quality of life within the first 6 months following hysterectomy compared to women with ovarian conservation. However, these differences were not apparent 2 years after surgery. II.Keywords
This publication has 25 references indexed in Scilit:
- Ovarian Conservation at the Time of Hysterectomy for Benign DiseaseObstetrics & Gynecology, 2005
- Hysterectomy and bilateral oophorectomy for severe premenstrual syndromeHuman Reproduction, 2004
- Androgens in womenThe Journal of Steroid Biochemistry and Molecular Biology, 2003
- Hormones, mood, sexuality, and the menopausal transitionFertility and Sterility, 2002
- Androgen deficiency in the oophorectomized womanFertility and Sterility, 2002
- Prohylactic oophorectomyInternational Journal of Gynecology & Obstetrics, 1999
- Incidence of symptom recurrence after hysterectomy for endometriosisFertility and Sterility, 1995
- The Role of Prophylactic Oophorectomy in Cancer PreventionGynecologic Oncology, 1994
- The Maine Womenʼs Health StudyObstetrics & Gynecology, 1994
- Bilateral oophorectomy and hysterectomy in the treatment of intractable pelvic pain associated with pelvic congestionBJOG: An International Journal of Obstetrics and Gynaecology, 1991