Crack Cocaine Use and Other Risk Factors for Tuberculin Positivity in Drug Users
Open Access
- 15 November 2002
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 35 (10), 1183-1190
- https://doi.org/10.1086/343827
Abstract
Two-step tuberculin testing and standardized interviews of 793 current and former drug users were performed to determine the risk factors for tuberculin positivity. The prevalence of tuberculin positivity was 25%. Factors independently associated with tuberculin positivity among participants seronegative for human immunodeficiency virus (HIV) included crack cocaine use (adjusted odds ratio [OR], 1.6; 95% confidence interval [CI], 1.0–2.5), employment as a home health aide (adjusted OR, 2.1; 95% CI, 1.0–4.1), birth in Puerto Rico (adjusted OR, 2.2; 95% CI, 1.3–3.6), foreign birthplace (adjusted OR, 4.7; 95% CI, 1.6–13.6), African American race (adjusted OR, 2.5; 95% CI, 1.2–5.0), reported tuberculosis exposure (adjusted OR, 2.3; 95% CI, 1.2–4.4), and older age (adjusted OR, 2.9; 95% CI, 1.2–6.7). Additional risk factors among HIV-infected participants included alcoholism (adjusted OR, 2.4; 95% CI, 1.0–5.8) and high CD4+ lymphocyte count. Identification of and administration of appropriate chemoprophylaxis to drug users with these risk factors should be given high priority.This publication has 22 references indexed in Scilit:
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