NVESD is currently researching relationships between facial thermal signatures and underlying physiological stress. This paper describes some of the initial findings of a study involving participants watching emotion-eliciting video clips while being monitored by a high-resolution, Mid-Wave InfraRed (MWIR), cooled sensor system. Both global and region-specific temperature profiles of the face were obtained for each participant from thermal videos recorded during the experiment. Changes in the global temperature patterns of each participant were shown to be consistent with changes in the visual and auditory stimuli. In some cases, there were inconsistencies in thermal trends among local facial regions of individual participants. This indicates the possibility that different regions may exhibit different thermal patterns in response to a stimulus.