Objectives: To determine if populations at high risk are receptive to tailored, multimedia interventions as a means of promoting adoption of health-protective behaviors related to STD prevention and control. Methods: Study participants (N=41) were exposed to the tailored, multimedia intervention and asked for feedback. Results: Participants were able to interact independently with the intervention. A majority found it engaging and indicated that their interaction with the intervention would change their future behavior. Conclusion: An urban, primarily African American sample of STD clinic patients was receptive to this tailored, multimedia intervention.