“Ten commandments” for the appropriate use of antibiotics by the practicing physician in an outpatient setting
Open Access
- 1 January 2011
- journal article
- research article
- Published by Frontiers Media SA in Frontiers in Microbiology
- Vol. 2, 230
- https://doi.org/10.3389/fmicb.2011.00230
Abstract
A multi-national working group on antibiotic stewardship, from the International Society of Chemotherapy, put together ten recommendations to physicians prescribing antibiotics to outpatients. These recommendations are: (1) use antibiotics only when needed; teach the patient how to manage symptoms of non-bacterial infections; (2) select the adequate ATB; precise targeting is better than shotgun therapy; (3) consider pharmacokinetics and pharmacodynamics when selecting an ATB; use the shortest ATB course that has proven clinical efficacy; (4) encourage patients’ compliance; (5) use antibiotic combinations only in specific situations; (6) avoid low quality and sub-standard drugs; prevent prescription changes at the drugstore; (7) discourage self-prescription; (8) follow only evidence-based guidelines; beware those sponsored by drug companies; (9) rely (rationally) upon the clinical microbiology lab; and (10) prescribe ATB empirically – but intelligently; know local susceptibility trends, and also surveillance limitations.This publication has 74 references indexed in Scilit:
- Generic Vancomycin Products Fail In Vivo despite Being Pharmaceutical Equivalents of the InnovatorAntimicrobial Agents and Chemotherapy, 2010
- Mutant Prevention Concentrations of Four Carbapenems against Gram-Negative RodsAntimicrobial Agents and Chemotherapy, 2010
- Comparative Study of the Mutant Prevention Concentrations of Moxifloxacin, Levofloxacin, and Gemifloxacin against PneumococciAntimicrobial Agents and Chemotherapy, 2010
- Factors Associated With Physicians’ Reliance on Pharmaceutical Sales RepresentativesAcademic Medicine, 2009
- Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post‐marketing clinical study on healthy volunteersBritish Journal of Clinical Pharmacology, 2009
- Effectiveness and safety of short vs. long duration of antibiotic therapy for acute bacterial sinusitis: a meta‐analysis of randomized trialsBritish Journal of Clinical Pharmacology, 2009
- Modeling antibiotic resistance in hospitals: The impact of minimizing treatment durationJournal of Theoretical Biology, 2007
- Exacerbations of chronic obstructive pulmonary disease: when are antibiotics indicated? A systematic reviewRespiratory Research, 2007
- Pharyngitis Management: Defining the ControversyJournal of General Internal Medicine, 2007
- Antibiotics as intermicrobial signaling agents instead of weaponsProceedings of the National Academy of Sciences of the United States of America, 2006