Intraventricular hemorrhage from ruptured aneurysm: clinical characteristics, complications, and outcomes in a large, prospective, multicenter study population
- 1 August 2007
- journal article
- research article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 107 (2), 261-265
- https://doi.org/10.3171/jns-07/08/0261
Abstract
Object In this study the authors analyzed the relationship of intraventricular hemorrhage (IVH) to in-hospital complications and clinical outcome in a large population of patients with aneurysmal subarachnoid hemorrhage (SAH). Methods Data from 3539 patients with aneurysmal SAH were evaluated, and these data were obtained from four prospective, randomized, double-blind, placebo-controlled trials of tirilazad that had been conducted between 1991 and 1997. Clinical characteristics, in-hospital complications, and outcome at 3 months post-SAH (Glasgow Outcome Scale score) were analyzed with regard to the presence or absence of IVH. Results Patients with SAH and IVH differ in demographic and admission characteristics from those with SAH but without IVH and are more likely to suffer in-hospital complications and a worse outcome at 3 months post-SAH. Conclusions The presence of IVH in patients with SAH has an important predictive value with regard to these aspects.Keywords
This publication has 33 references indexed in Scilit:
- Influence of intraventricular hemorrhage on outcome after rupture of intracranial aneurysmNeurosurgical Review, 2001
- Effect of Cisternal and Ventricular Blood on Risk of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage:Stroke, 2001
- Differential Expression of HSC73 and HSP72 mRNA and Proteins between Young and Adult Gerbils after Transient Cerebral Ischemia: Relation to Neuronal VulnerabilityJournal of Cerebral Blood Flow & Metabolism, 2000
- A randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North AmericaJournal of Neurosurgery, 1997
- Randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in Europe, Australia, and New ZealandJournal of Neurosurgery, 1996
- Outcome in patients with large intraventricular haemorrhages: a volumetric study.Journal of Neurology, Neurosurgery & Psychiatry, 1995
- Amount of blood on computed tomography as an independent predictor after aneurysm rupture.Stroke, 1993
- Clinical Analysis of a Series of Vertebral Aneurysm CasesNeurosurgery, 1992
- Prediction of delayed cerebral ischemia, rebleeding, and outcome after aneurysmal subarachnoid hemorrhage.Stroke, 1988
- ASSESSMENT OF OUTCOME AFTER SEVERE BRAIN DAMAGE A Practical ScaleThe Lancet, 1975