Synthesis of some 1-(dihydroxypropyl)pyrazolo[3,4-d]-pyrimidines and in vivo evaluation of their antileishmanial and antitrypanosomal activity
- 30 June 1990
- journal article
- Published by Elsevier BV in European Journal of Medicinal Chemistry
- Vol. 25 (5), 419-424
- https://doi.org/10.1016/0223-5234(90)90005-n
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- A new Leishmania infantum enzymatic variant, agent of an urban visceral case unresponsive to drugsTransactions of the Royal Society of Tropical Medicine and Hygiene, 1987
- Synthesis and antiherpes simplex virus activity of 9-[(1,3-dihydroxy-2-propylthio)methyl]guanineJournal of Medicinal Chemistry, 1985
- Pyrazolopyrimidine metabolism in the pathogenic trypanosomatidaeMolecular and Biochemical Parasitology, 1983
- Evaluation of allopurinol in the treatment of kala-azar occurring in North Bihar, IndiaTransactions of the Royal Society of Tropical Medicine and Hygiene, 1983
- Comparative effects of 4-aminopyrazolopyrimidine, its 2'-deoxyriboside derivative, and allopurinol on in vitro growth of American Leishmania speciesAntimicrobial Agents and Chemotherapy, 1982
- Allopurinol in the treatment of visceral leishmaniasisTransactions of the Royal Society of Tropical Medicine and Hygiene, 1981
- The experimental chemotherapy of leishmaniasis, IVPathogens and Global Health, 1980
- ( S )-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral ActivityScience, 1978
- Stereospecific synthesis of D-1-fluorodeoxyglycerol 3-phosphate and its effects on glycerol 3-phosphate dehydrogenaseBiochemistry, 1971
- Potential Purine Antagonists. I. Synthesis of Some 4,6-Substituted Pyrazolo [3,4-d] pyrimidines1Journal of the American Chemical Society, 1956