Specificity of immobilized porcine pepsin in H/D exchange compatible conditions
- 26 March 2008
- journal article
- research article
- Published by Wiley in Rapid Communications in Mass Spectrometry
- Vol. 22 (7), 1041-1046
- https://doi.org/10.1002/rcm.3467
Abstract
Statistical analysis of data from 39 proteins (13 766 amino acid residues) digested with immobilized porcine pepsin under conditions compatible with hydrogen/deuterium (H/D) exchange (et al. (14.8%). This is due, in part, to the larger protein sizes used in the current study. While the specificity of pepsin was similar to that previously observed, higher selectivity was observed in the present study due to less experimental variation in the conditions used to generate our database. Copyright © 2008 John Wiley & Sons, Ltd.Keywords
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