Effect of chloropromazine on "aggressive" responding in the rat.

Abstract

The increase in rate of responding seen at the onset of extinction was used as a measure of aggression. Rats learned to press a lever for water on a regular-reinforcement schedule. Half received injections of chlorpromazine, and then all Ss were given 6 min. of regular reinforcement followed by 3 min. of extinction. On the test trial the injected group made fewer responses than controls during both reinforcement and extinction, but they showed a relatively greater increase in rate of response after the onset of extinction. From Psyc Abstracts 36:04:4DK98T. (PsycINFO Database Record (c) 2006 APA, all rights reserved)