Integrin αIIbβ3 Activation in Chinese Hamster Ovary Cells and Platelets Increases Clustering Rather than Affinity
Open Access
- 1 January 2010
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 285 (3), 1841-1849
- https://doi.org/10.1074/jbc.m109.057349
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragmentThe Journal of cell biology, 2009
- Differences in Regulation ofDrosophilaand Vertebrate Integrin Affinity by TalinMolecular Biology of the Cell, 2008
- Structural Basis for the Autoinhibition of Talin in Regulating Integrin ActivationMolecular Cell, 2008
- Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3The Journal of cell biology, 2008
- Integrin activationBiochemical Society Transactions, 2008
- Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivoThe Journal of Experimental Medicine, 2007
- Talin is required for integrin-mediated platelet function in hemostasis and thrombosisThe Journal of Experimental Medicine, 2007
- Structural Basis of Integrin Regulation and SignalingAnnual Review of Immunology, 2007
- IntegrinsCell, 2002
- Integrin Activation Involves a Conformational Change in the α1 Helix of the β Subunit A-domainJournal of Biological Chemistry, 2002