BRCA1andBRCA2Mutation Testing in Young Women With Breast Cancer

Abstract

Breast cancer is the most common cancer diagnosed in women younger than 40 years in the United States.¹ Because BRCA1 (OMIM 113705) and BRCA2 (OMIM 600185) mutation carriers are at increased risk for developing early-onset breast cancer, the National Comprehensive Cancer Network (NCCN) guidelines recommend that women diagnosed as having breast cancer at 50 years or younger undergo genetic testing.²