Effect of twisting on the behavior of a double-stranded polymer chain: A Monte Carlo simulation
- 22 November 1999
- journal article
- Published by AIP Publishing in The Journal of Chemical Physics
- Vol. 111 (20), 9424-9433
- https://doi.org/10.1063/1.480035
Abstract
DNA and some proteins have a multistranded chain structure and exhibit characteristic tertiary structures due to twisting or anisotropic rigidity. We studied the effect of chain twisting on the behavior of a circular double-stranded polymer chain using a Monte Carlo simulation with bond fluctuation model. We found that there are two regimes for the chain conformation, depending on its twisting. In the first regime, with weak twisting, a circular chain behaves like a coiled linear chain. In the second regime, the chain shows scaling dependencies characterized by supercoiled structures.Keywords
This publication has 27 references indexed in Scilit:
- Atomic force microscopy of supercoiled DNA structure on micaAnalytica Chimica Acta, 1998
- Molecular dynamics simulations of small DNA plasmids: Effects of sequence and supercoiling on intramolecular motionsPeptide Science, 1996
- Molecular modeling of closed circular DNA thermodynamic ensemblesPeptide Science, 1996
- Light scattering studies of supercoiled and nicked DNAPeptide Science, 1996
- The Twist, Writhe and Overall Shape of Supercoiled DNA Change During Counterion-induced Transition from a Loosely to a Tightly Interwound SuperhelixJournal of Molecular Biology, 1994
- Structure of plectonemically supercoiled DNAJournal of Molecular Biology, 1990
- Elastic model of highly supercoiled DNAPeptide Science, 1986
- Calculation of the twist and the writhe for representative models of DNAJournal of Molecular Biology, 1986
- Torsional rigidity of DNA and length dependence of the free energy of DNA supercoilingJournal of Molecular Biology, 1984
- Concept of quasimonomers and its application to some problems of polymer statisticsPolymer, 1978