Tuberculosis and AIDS Co-Morbidity in Children: Linkage of Databases from Espirito Santo State, Brazil
Open Access
- 28 September 2010
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Tropical Pediatrics
- Vol. 57 (4), 296-298
- https://doi.org/10.1093/tropej/fmq087
Abstract
We assessed the prevalence of AIDS among children diagnosed with active tuberculosis (TB) in Espírito Santo State, Brazil, by linking TB and AIDS surveillance databases using Reclink software and SPSS. Among 411 pediatric TB cases from 2000 to 2006, 27 (7%) were co-infected with AIDS. Most children were unable to provide a sputum specimen; co-infected patients were more likely to be smear negative for acid-fast bacilli (83% vs 46%; p = 0.07) and culture positive for Mycobacterium tuberculosis (44% vs 19%; p < 0.001). In all, 57% of co-infected patients did not react to tuberculin skin test compared with 17% of TB patients (p < 0.001). This report emphasizes the significance of AIDS in pediatric TB cases and highlights the importance of evaluating surveillance databases for gaining a better understanding of the burden of co-infection.Keywords
This publication has 5 references indexed in Scilit:
- High Incidence of Tuberculosis among HIV‐Infected Infants: Evidence from a South African Population‐Based Study Highlights the Need for Improved Tuberculosis Control StrategiesClinical Infectious Diseases, 2009
- Diagnostic and Management Challenges for Childhood Tuberculosis in the Era of HIVThe Journal of Infectious Diseases, 2007
- Faculty Opinions recommendation of Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings.Published by H1 Connect ,2006
- Tuberculosis and HIV co-infection in children under 15 years of age in Rio de Janeiro, Brazil.2003
- [Diagnosis and treatment of tuberculosis in children--an updated review of an old problem].Jornal de Pediatria, 2002