X‐linked retinoschisis is closely linked to DXS41 and DXS16 but not DXS85
- 1 September 1987
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 32 (3), 192-195
- https://doi.org/10.1111/j.1399-0004.1987.tb03353.x
Abstract
A linkage of study was carried out in nine families with 24 males affected by X-linked recessive retinoschisis (RS), using three polymorphic DNA probes from the distal segment of Xp. Close linkage of the disease locus with markers DXS41 (probe p99-6) and DXS16 (pXUT23) was found, confirming the location of the RS gene on the distal short arm of the X chromosome. Lod scores for linkage with DXS85 (probe 782) were negative.Keywords
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