Recurrence risks in complex inheritance with special regard to pyloric stenosis.
- 1 December 1977
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 14 (6), 408-414
- https://doi.org/10.1136/jmg.14.6.408
Abstract
A large body of data on segregating families is used to generate specific recurrence risks conditional on sex and birth order for the best-fitting model of polygenes plus maternal effect. The method is general for diseases of complex inheritance, and lies within the competence of any serious genetic clinic. The question of whether consultees demand as much specificity should be subordinate to the question of whether counsellors are justified in providing less.This publication has 35 references indexed in Scilit:
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