Expression of the Major Histocompatibility Complex Class I Molecule Mamu-A*01 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication
Open Access
- 15 February 2003
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 77 (4), 2736-2740
- https://doi.org/10.1128/jvi.77.4.2736-2740.2003
Abstract
Several HLA alleles are associated with attenuated human immunodeficiency virus disease progression. We explored the relationship between the expression of particular major histocompatibility complex (MHC) class I alleles and viremia in simian immunodeficiency virus SIVmac239-infected macaques. Of the common MHC class I alleles, animals that expressed Mamu-A*01 exhibited the best control of viral replication.Keywords
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