p85α SH2 Domain Phosphorylation by IKK Promotes Feedback Inhibition of PI3K and Akt in Response to Cellular Starvation
- 16 February 2012
- journal article
- research article
- Published by Elsevier BV in Molecular Cell
- Vol. 45 (6), 719-730
- https://doi.org/10.1016/j.molcel.2012.01.010
Abstract
No abstract availableThis publication has 39 references indexed in Scilit:
- Regulation and Function of IKK and IKK-Related KinasesScience's STKE, 2006
- Phosphoinositide 3-kinase regulatory subunit p85α suppresses insulin action via positive regulation of PTENProceedings of the National Academy of Sciences of the United States of America, 2006
- The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismNature Reviews Genetics, 2006
- Glycogen Synthase Kinase 3β Functions To Specify Gene-Specific, NF-κB-Dependent TranscriptionMolecular and Cellular Biology, 2005
- Then Negative Regulation of Phosphoinositide 3-Kinase Signaling by p85 and Its Implication in CancerCell Cycle, 2005
- The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complexThe Journal of cell biology, 2005
- ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell linesProceedings of the National Academy of Sciences of the United States of America, 2005
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR ComplexScience, 2005
- Crystal structure of the C-terminal SH2 domain of the p85α regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrateJournal of Molecular Biology, 1999
- Regulation of the p85/p110α Phosphatidylinositol 3′-KinaseOnline Journal of Public Health Informatics, 1998