Change in quality of life: a follow up study among patients with HIV infection with and without TB in Ethiopia
Open Access
- 29 April 2013
- journal article
- Published by Springer Science and Business Media LLC in BMC Public Health
- Vol. 13 (1), 1-6
- https://doi.org/10.1186/1471-2458-13-408
Abstract
There is a dearth of literature on the impact of TB/HIV co-infection on quality of life (QoL). We conducted a study to assess the change in QoL over a 6-months period and its predictors among HIV-infected patients with and without TB in Ethiopia. 465 HIV-infected patients without TB and 124 TB/HIV co-infected patients were enrolled in a prospective study in February, 2009. 455 (98%) HIV-infected and 97 (78%) TB/HIV co-infected patients were followed for 6 months. Data on QoL at baseline and 6th month were collected by trained nurses through face to face interviews using the short Amharic version of the World Health Organization Quality of Life Instrument for HIV clients (WHOQOL HIV-Brief). Common Mental Disorder (CMD) was assessed using a validated version of the Kessler-10 scale. Multivariate analysis was conducted using generalized estimating equations (GEE) using STATA to assess change in QoL and its predictors. There was a statistically significant improvement of the physical, psychological, social, environmental and spiritual QoL at the 6th months follow up compared to the baseline for both groups of patients (P < 0.0001). The change in QoL in all dimension were more marked for TB/HIV co-infected patients compared to HIV-infected patients without TB. A severe form of CMD was strongly associated with poorer physical QoL among TB/HIV co-infected individuals (β = −2.84; P = 0.000) and HIV clients without TB (β = −2.34; P = 0.000). This study reveals that ART and anti-TB treatment significantly improve the QoL particularly among TB/HIV co-infected patients. We recommend that the ministry of health in collaboration with partners shall integrate mental health services into the TB/HIV programs and train health care providers to timely identify and treat CMD to improve QoL.Keywords
This publication has 23 references indexed in Scilit:
- Employment status is associated with both physical and mental health quality of life in people living with HIVAIDS Care, 2011
- Quality of life in people living with HIV/AIDS in LebanonAIDS Care, 2010
- Tuberculosis and HIV co-infection: its impact on quality of lifeHealth and Quality of Life Outcomes, 2009
- Measuring health-related quality of life in tuberculosis: a systematic reviewHealth and Quality of Life Outcomes, 2009
- Cognitive impairment and preferences for current healthHealth and Quality of Life Outcomes, 2009
- The mental health consequences of intimate partner violence against women in Agaro Town, southwest EthiopiaTropical Doctor, 2008
- Trends and predictors of quality of life among HIV-infected adults taking highly active antiretroviral therapy in rural UgandaAIDS Care, 2007
- Predictors of Changes in Health-Related Quality of Life Among Men with HIV Infection in the HAART EraAIDS Patient Care and STDs, 2005
- Preliminary development of the World Health Organsiation's Quality of Life HIV instrument (WHOQOL-HIV): analysis of the pilot versionSocial Science & Medicine, 2003
- Highly Active Antiretroviral Treatment (HAART) and Health-Related Quality of Life in Naive and Pretreated HIV-Infected PatientsHIV Research & Clinical Practice, 2001