Smoking cessation increases gingival blood flow and gingival crevicular fluid
- 9 March 2004
- journal article
- research article
- Published by Wiley in Journal of Clinical Periodontology
- Vol. 31 (4), 267-272
- https://doi.org/10.1111/j.1600-051x.2004.00476.x
Abstract
Objectives: The purpose of the present study was to determine the effect of smoking cessation on gingival blood flow (GBF) and gingival crevicular fluid (GCF). Material and Methods: Sixteen male smokers (aged 22–39 (25.3±4.0) years), with no clinical signs of periodontal and systemic diseases, were recruited. The experiment was performed before (baseline) and at 1, 3 and 5 days, and at 1, 2, 4 and 8 weeks after smoking cessation. The status of smoking and smoking cessation was verified by exhaled carbon monoxide (CO) concentration, and by serum nicotine and cotinine concentrations. A laser Doppler flowmeter was used to record relative blood flow continuously, on three gingival sites of the left maxillary central incisor (mid‐labial aspect of the gingival margin and bilateral interdental papillae). The GCF was collected at the mesio‐ and disto‐labial aspects of the left maxillary central incisor and the volume was calculated by the Periotron 6000® system. The same measurements except for the GBF were performed on 11 non‐smoking controls (four females and seven males), aged 23–27 (24.4±1.2) years. Results: Eleven of 16 smokers successfully completed smoking cessation for 8 weeks. At 1 day after smoking cessation, there was a significantly lower CO concentration than at baseline (pppp<0.01). Conclusion: The results show that the gingival microcirculation recovers to normal in the early stages of smoking cessation, which could activate the gingival tissues metabolism/remodeling, and contribute to periodontal health.Keywords
This publication has 40 references indexed in Scilit:
- Smoking cessation strategies and periodontal disease in young adultsBritish Dental Journal, 2002
- Smoking cessation strategies and periodontal disease in young adultsBritish Dental Journal, 2002
- Pocket Oxygen Tension in Smokers and Non‐Smokers With Periodontal DiseaseThe Journal of Periodontology, 2000
- The Association Between Smoking Cessation and Periodontal Status and Salivary Proteinase LevelsThe Journal of Periodontology, 1999
- Vascular damage from smoking: disease mechanisms at the arterial wallVascular Medicine, 1998
- The Effect of Nicotine on the Attachment of Human Fibroblasts to Glass and Human Root Surfaces in VitroThe Journal of Periodontology, 1988
- The effect of non-surgical treatment on periodontal pockets in smokers and non-smokersJournal of Clinical Periodontology, 1986
- Tobacco Smoke Toxicity: Loss of Human Oral Leukocyte Function and Fluid-Cell MetabolismScience, 1969