Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice
- 1 December 1978
- journal article
- research article
- Published by Springer Science and Business Media LLC in Immunogenetics
- Vol. 7 (1), 17-24
- https://doi.org/10.1007/bf01843983
Abstract
The unresponsiveness to LPS detected in C57BL/10Cr mice is inherited as a recessive trait and is determined by an autosomal gene linked to theMup-1 locus on chromosome 4. Since no complementation for LPS responsiveness was observed in F1 hybrid mice between C3H/HeJ and C57BL/10Cr, we conclude that C57BL/10Cr mice carry a defective allele at the sameLps locus, previously identified by the mutation detected in the C3H/HeJ strain.This publication has 30 references indexed in Scilit:
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