Nocturnal Penile Tumescence and Rigidity Evaluation in Men with Epilepsy
- 1 December 1996
- Vol. 37 (12), 1211-1214
- https://doi.org/10.1111/j.1528-1157.1996.tb00555.x
Abstract
Men with epilepsy appear to have an approximately fivefold increase in risk of erectile dysfunction (ED). We attempted to determine whether ED in men with epilepsy was due to a physiological basis and whether erectile function could be adequately evaluated with an ambulatory nocturnal penile tumescence and rigidity monitor. The physiologic integrity of the sexual response in men with epilepsy and ED was assessed with an ambulatory nocturnal penile tumescence and rigidity monitor (NPTR). Six men with localization-related epilepsy of temporal lobe origin (TLE) and ED, 2 men with TLE and normal sexual function, and 1 man with nonepileptic seizures (NES) and ED underwent evaluation of nocturnal erections for at least 2 nights. Five of 6 men with TLE and complaints of ED had abnormal ambulatory NPTR evaluations. All others had normal ambulatory NPTR. All abnormal evaluations showed reduced levels of rigidity, often with normal levels of tumescence. Previous studies have shown this abnormal ambulatory NPTR pattern to be associated with neurogenic rather than vasogenic ED. Therefore, epilepsy-related ED may have a substantial neurophysiologic component.This publication has 29 references indexed in Scilit:
- Sexual behaviour in a centre for epilepsyActa Neurologica Scandinavica, 2009
- Sexuality and Chronic Illness: Biopsychosocial ApproachSeminars in Neurology, 1992
- Characteristics of Penile Erections During Sleep Recorded from Normal SubjectsJournal of Clinical Neurophysiology, 1992
- Sexual Dysfunction in EpilepsyEpilepsia, 1991
- Central effect of yohimbine on sexual behavior in the ratPhysiology & Behavior, 1990
- Comparison of Carbamazepine, Phenobarbital, Phenytoin, and Primidone in Partial and Secondarily Generalized Tonic–Clonic SeizuresThe New England Journal of Medicine, 1985
- Sexual Disturbances in Temporal Lobe Epilepsy: A Controlled StudyThe British Journal of Psychiatry, 1979
- Sex in lasting marriages: A longitudinal studyThe Journal of Sex Research, 1977
- Changes of sexual behavior related to temporal lobe disorders in man∗The Journal of Sex Research, 1970
- IMPOTENCE IN PATIENTS WITH TEMPORAL-LOBE LESIONSThe Lancet, 1966