Postoperative Endophthalmitis
Open Access
- 15 February 2004
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 38 (4), 542-546
- https://doi.org/10.1086/381262
Abstract
Postoperative endophthalmitis remains a serious clinical problem in ophthalmology, with an incidence of ∼0.5%. Prognosis is largely determined by the virulence of the offending organism. The Endophthalmitis Vitrectomy Study (EVS) was a prospective, randomized trial comparing various diagnostic and treatment modalities in cases of endophthalmitis that followed cataract surgery. The EVS found that vitrectomy was only beneficial for patients presenting with very poor visual acuity and that intravenous antibiotic treatments had no additional benefit, compared with intravitreal antibiotic therapy alone. However, weaknesses of the EVS leave these conclusions open to modification in the future. Preoperative application of povidone-iodine preparation to the skin and conjunctiva is the only proven endophthalmitis prophylaxis. Endophthalmitis may be chronic and may follow glaucoma surgery and intravitreal injection of gas and drugs. The EVS did not study these issues, although they are associated with specific features that may require alterations in patient management.This publication has 30 references indexed in Scilit:
- Topical anaesthesia: a risk factor for post‐cataract‐extraction endophthalmitis?Clinical & Experimental Ophthalmology, 2003
- Bacterial endophthalmitis after small-incision cataract surgeryJournal of Cataract & Refractive Surgery, 2003
- OFFICE-BASED SUTURELESS TRANSCONJUNCTIVAL PARS PLANA VITRECTOMYRetina, 2002
- EVALUATING OUTPATIENT VERSUS INPATIENT COSTS IN ENDOPHTHALMITIS MANAGEMENTRetina, 2002
- Do we heed the Endophthalmitis Vitrectomy Study in Canada?Canadian Journal of Ophthalmology, 2002
- Vitreous hemorrhage as the initial presentation of postoperative endophthalmitisAmerican Journal of Ophthalmology, 2002
- Diabetes and postoperative endophthalmitis in the endophthalmitis vitrectomy study.American Journal of Ophthalmology, 2001
- Endophthalmitis after penetrating ocular traumaCurrent Opinion in Opthalmology, 1997
- Results of the Endophthalmitis Vitrectomy StudyAmerican Journal of Ophthalmology, 1995
- Chemical Preparation of the Eye in Ophthalmic SurgeryAmerican Journal of Ophthalmology, 1984