The Case for Using Hydrogen Peroxide Contact Lens Care Solutions: A Review
- 1 March 2019
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Eye & Contact Lens: Science & Clinical Practice
- Vol. 45 (2), 69-82
- https://doi.org/10.1097/icl.0000000000000542
Abstract
Despite their established disinfection and safety benefits, the use of hydrogen peroxide (H2O2) lens care systems among today's wearers of reusable contact lenses remains low in comparison with multipurpose solution (MPS) use. Multipurpose solution systems, however, present several potential drawbacks that may impact patient outcomes, including the use of chemical preservatives for disinfection, biocompatibility issues, and challenges with respect to lens care compliance. Given their unique composition and mechanism of action, one-step H2O2 systems offer the opportunity to avoid many of the challenges associated with MPS use. This article reviews the evolution of H2O2 lens care systems and examines the current scientific and clinical evidence regarding the relative ease of use, lens and tissue compatibility, disinfection efficacy, and ocular surface safety of H2O2 systems. Evaluation of the available data indicates that in comparison with MPS, one-step H2O2 systems tend to promote more favorable compliance, efficacy, comfort, and ocular surface outcomes for a wide range of contact lens–wearing patients. Based on the current published evidence, the authors recommend that eye care practitioners consider making one-step H2O2 systems their first-line contact lens care recommendation for most wearers of reusable lenses.Keywords
This publication has 88 references indexed in Scilit:
- In-vitroanalysis of the microbicidal activity of 6 contact lens care solutionsBMC Infectious Diseases, 2012
- Estimating the Annual Economic Burden of Illness Caused by Contact Lens–Associated Corneal Infiltrative Events in the United StatesEye & Contact Lens: Science & Clinical Practice, 2012
- Non-Compliance with Contact Lens Wear and Care Practices: A Comparative AnalysisOptometry and Vision Science, 2011
- Risk Factors for Corneal Infiltrative Events during Continuous Wear of Silicone Hydrogel Contact LensesInvestigative Ophthalmology & Visual Science, 2010
- Patient Compliance During Contact Lens Wear: Perceptions, Awareness, and BehaviorEye & Contact Lens: Science & Clinical Practice, 2010
- Accidental self-induced chemical eye injury in patients with low visionEye, 2010
- National Outbreak ofAcanthamoebaKeratitis Associated with Use of a Contact Lens Solution, United StatesEmerging Infectious Diseases, 2009
- Resistance of Acanthamoeba Cysts to Disinfection in Multiple Contact Lens SolutionsJournal of Clinical Microbiology, 2009
- Contact Lens Solution Efficacy Against Acanthamoeba castellaniEye & Contact Lens: Science & Clinical Practice, 2007
- The Association of Contact Lens Solution Use and Acanthamoeba KeratitisAmerican Journal of Ophthalmology, 2007