Body Loadings and Health Risk Assessment of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans at an Intensive Electronic Waste Recycling Site in China

Abstract

This study is one of the very few investigating the dioxin body burden of a group of child-bearing-aged women at an electronic waste (e-waste) recycling site (Taizhou, Zhejiang Province) (24 ± 2.83 years of age, 40% were primiparae) and a reference site (Lin'an city, Zhejiang Province, about 245 km away from Taizhou) (24 ± 2.35 years of age, 100% were primiparae) in China. Five sets of samples (each set consisted of human milk, placenta, and hair) were collected from each site. Body burdens of people from the e-waste processing site (human milk, 21.02 ± 13.81 pg WHO-TEQ₁₉₉₈/g fat (World Health Organization toxic equivalency 1998); placenta, 31.15 ± 15.67 pg WHO-TEQ₁₉₉₈/g fat; hair, 33.82 ± 17.74 pg WHO-TEQ₁₉₉₈/g dry wt) showed significantly higher levels of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) than those from the reference site (human milk, 9.35 ± 7.39 pg WHO-TEQ₁₉₉₈/g fat; placenta, 11.91 ± 7.05 pg WHO-TEQ₁₉₉₈/g fat; hair, 5.59 ± 4.36 pg WHO-TEQ₁₉₉₈/g dry wt) and were comparatively higher than other studies. The difference between the two sites was due to e-waste recycling operations, for example, open burning, which led to high background levels. Moreover, mothers from the e-waste recycling site consumed more foods of animal origin. The estimated daily intake of PCDD/Fs within 6 months by breast-fed infants from the e-waste processing site was 2 times higher than that from the reference site. Both values exceeded the WHO tolerable daily intake for adults by at least 25 and 11 times, respectively. Our results implicated that e-waste recycling operations cause prominent PCDD/F levels in the environment and in humans. The elevated body burden may have health implications for the next generation.