Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum
- 1 January 2000
- journal article
- research article
- Published by Informa UK Limited in Xenobiotica
- Vol. 30 (6), 609-617
- https://doi.org/10.1080/004982500406435
Abstract
1. Resveratrol, a polyphenolic compound present in grapes and wine, has beneficial effects against cancer and protective effects on the cardiovascular system. It is present in the diet, and the hepatic and duodenal sulphation might limit the bioavailability of this compound. The aim was to study the sulphation of resveratrol in the human liver and duodenum. 2. A simple and reproducible radiometric assay for resveratrol sulphation was developed. It employed 3'-phosphoadenosine-5'-phosphosulphate-[35Keywords
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