Core‐Shell Nanocapsules Stabilized by Single‐Component Polymer and Nanoparticles for Magneto‐Chemotherapy/Hyperthermia with Multiple Drugs
- 12 June 2012
- journal article
- research article
- Published by Wiley in Advanced Materials
- Vol. 24 (27), 3627-3632
- https://doi.org/10.1002/adma.201201251
Abstract
Iron-oxide-containing double emulsion capsules carrying both hydrophilic and hydrophobic therapeutic molecules can deliver drugs and energy on demand in vivo. Magneto-chemotherapy/hyperthermia involves a burst-like release of hydrophilic doxorubicin and hydrophobic paclitaxel, remotely triggered by a high frequency magnetic field, which also releases energy via internalized iron oxide nanoparticles, all contributing to cell kill.Keywords
This publication has 26 references indexed in Scilit:
- Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and DoxorubicinACS Nano, 2011
- The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayersNature Materials, 2011
- PLGA/polymeric liposome for targeted drug and gene co-deliveryBiomaterials, 2010
- Microfluidic Melt Emulsification for Encapsulation and Release of ActivesACS Applied Materials & Interfaces, 2010
- Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell LineACS Nano, 2010
- pH-Sensitive degradable polymersomes for triggered release of anticancer drugs: A comparative study with micellesJournal of Controlled Release, 2010
- Co-delivery of drugs and DNA from cationic core–shell nanoparticles self-assembled from a biodegradable copolymerNature Materials, 2006
- Pharmacokinetics of combined doxorubicin and paclitaxel in miceCancer Letters, 2005
- Cisplatin, paclitaxel and escalating doses of doxorubicin (TAP) in advanced ovarian cancer: a phase I trial.Japanese Journal of Clinical Oncology, 2004
- Cardioprotection by dexrazoxane in rats treated with doxorubicin and paclitaxelCancer Chemotherapy and Pharmacology, 1999