Representation of Three-Dimensional Space in the Hippocampus of Flying Bats
- 19 April 2013
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 340 (6130), 367-372
- https://doi.org/10.1126/science.1235338
Abstract
Many animals, on air, water, or land, navigate in three-dimensional (3D) environments, yet it remains unclear how brain circuits encode the animal's 3D position. We recorded single neurons in freely flying bats, using a wireless neural-telemetry system, and studied how hippocampal place cells encode 3D volumetric space during flight. Individual place cells were active in confined 3D volumes, and in >90% of the neurons, all three axes were encoded with similar resolution. The 3D place fields from different neurons spanned different locations and collectively represented uniformly the available space in the room. Theta rhythmicity was absent in the firing patterns of 3D place cells. These results suggest that the bat hippocampus represents 3D volumetric space by a uniform and nearly isotropic rate code.Keywords
This publication has 28 references indexed in Scilit:
- Large-scale navigational map in a mammalProceedings of the National Academy of Sciences of the United States of America, 2011
- Anisotropic encoding of three-dimensional space by place cells and grid cellsNature Neuroscience, 2011
- Dynamics of hippocampal spatial representation in echolocating batsHippocampus, 2011
- Spatial Representation along the Proximodistal Axis of CA1Neuron, 2010
- Development of the Hippocampal Cognitive Map in Preweanling RatsScience, 2010
- Intracellular dynamics of hippocampal place cells during virtual navigationNature, 2009
- Unmasking the CA1 Ensemble Place Code by Exposures to Small and Large Environments: More Place Cells and Multiple, Irregularly Arranged, and Expanded Place Fields in the Larger SpaceJournal of Neuroscience, 2008
- What the bat's voice tells the bat's brainProceedings of the National Academy of Sciences of the United States of America, 2008
- Cellular networks underlying human spatial navigationNature, 2003
- Dynamics of the Hippocampal Ensemble Code for SpaceScience, 1993