VAD as Bridge to Recovery in Anthracycline-Induced Cardiomyopathy and HHV6 Myocarditis
- 1 September 2014
- journal article
- case report
- Published by American Academy of Pediatrics (AAP)
- Vol. 134 (3), e894-e899
- https://doi.org/10.1542/peds.2013-2272
Abstract
This report describes an 8-year-old child with acute anthracycline-induced cardiomyopathy triggered by human herpesvirus 6 and the subsequent implantation of an intracorporeal continuous-flow left ventricular assist device (LVAD) and the process to discharge the child from the hospital. After barely 3 months on mechanical support, the device was explanted after thorough examination. Experiences regarding LVAD removal are limited, and no guidelines for echocardiographic and hemodynamic criteria for LVAD removal in children have been published thus far. We present our institutional algorithm for device selection, surveillance in an ambulatory setting, and testing for myocardial recovery, as well as our criteria for LVAD explantation in children.Keywords
This publication has 19 references indexed in Scilit:
- First Experiences With the HeartWare Ventricular Assist System in ChildrenThe Annals of Thoracic Surgery, 2011
- What is the ideal off-test trial for continuous-flow ventricular-assist-device explantation? Intracircuit back-flow analysis in a mock circulation modelJournal of Artificial Organs, 2011
- A structured 3-step approach to evaluate cardiac recovery with continuous flow circulatory supportThe Journal of Heart and Lung Transplantation, 2010
- Initial clinical experience with a novel left ventricular assist device with a magnetically levitated rotor in a multi-institutional trialThe Journal of Heart and Lung Transplantation, 2010
- Heart failure reversal by ventricular unloading in patients with chronic cardiomyopathy: criteria for weaning from ventricular assist devicesEuropean Heart Journal, 2010
- Doxorubicin CardiomyopathyJMIR AI, 2009
- Human herpes virus 6 in archival cardiac tissues from children with idiopathic dilated cardiomyopathy or congenital heart diseaseJournal of Clinical Pathology, 2008
- Cardiotoxic drugs: clinical monitoring and decision makingHeart, 2008
- Left Ventricular Assist Device and Drug Therapy for the Reversal of Heart FailureNew England Journal of Medicine, 2006
- Bridging to transplantability with a ventricular assist deviceThe Journal of Thoracic and Cardiovascular Surgery, 2005