The Association Between Childhood Trauma and Memory Functioning in Schizophrenia
- 13 September 2009
- journal article
- Published by Oxford University Press (OUP) in Schizophrenia Bulletin
- Vol. 37 (3), 531-537
- https://doi.org/10.1093/schbul/sbp096
Abstract
Both neurocognitive impairments and a history of childhood abuse are highly prevalent in patients with schizophrenia. Childhood trauma has been associated with memory impairment as well as hippocampal volume reduction in adult survivors. The aim of the following study was to examine the contribution of childhood adversity to verbal memory functioning in people with schizophrenia.Eighty-five outpatients with a Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) diagnosis of chronic schizophrenia were separated into 2 groups on the basis of self-reports of childhood trauma. Performance on measures of episodic narrative memory, list learning, and working memory was then compared using multivariate analysis of covariance.Thirty-eight (45%) participants reported moderate to severe levels of childhood adversity, while 47 (55%) reported no or low levels of childhood adversity. After controlling for premorbid IQ and current depressive symptoms, the childhood trauma group had significantly poorer working memory and episodic narrative memory. However, list learning was similar between groups.Childhood trauma is an important variable that can contribute to specific ongoing memory impairments in schizophrenia.Keywords
This publication has 41 references indexed in Scilit:
- Cognitive predictors of symptom change for participants in vocational rehabilitationSchizophrenia Research, 2007
- Environment and Schizophrenia: Environmental Factors in Schizophrenia: Childhood Trauma--A Critical ReviewSchizophrenia Bulletin, 2006
- Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implicationsActa Psychiatrica Scandinavica, 2005
- Vocational function among persons with schizophrenia with and without history of childhood sexual traumaJournal of Traumatic Stress, 2004
- MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress DisorderAmerican Journal of Psychiatry, 2003
- Childhood Sexual Trauma and Psychosocial Functioning in Adults With SchizophreniaPsychiatric Services, 2001
- Reliability of reports of violent victimization and posttraumatic stress disorder among men and women with serious mental illnessJournal of Traumatic Stress, 1999
- Episodic memory and learning in patients with chronic schizophreniaSchizophrenia Research, 1999
- Lateralization of verbal memory and unilateral hippocampal sclerosis: Evidence of task-specific effectsJournal of Clinical and Experimental Neuropsychology, 1993
- Memory Function in Focal Epilepsy: A Comparison of Non-Surgical, Unilateral Temporal Lobe and Frontal Lobe SamplesCortex, 1980