Continuous microfluidic immunomagnetic cell separation
- 22 November 2004
- journal article
- Published by AIP Publishing in Applied Physics Letters
- Vol. 85 (21), 5093-5095
- https://doi.org/10.1063/1.1823015
Abstract
We present a continuous-flow microfluidic device that enables cell by cell separation of cells selectively tagged with magnetic nanoparticles. The cells flow over an array of microfabricated magnetic stripes, which create a series of high magnetic field gradients that trap the magnetically labeled cells and alter their flow direction. The process was observed in real time using a low power microscope. The device has been demonstrated by the separation of leukocytes from whole human blood.3 page(sKeywords
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