Synthesis and Evaluation of Novel Inhibitors of Pim-1 and Pim-2 Protein Kinases
- 15 December 2008
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 52 (1), 74-86
- https://doi.org/10.1021/jm800937p
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- The selectivity of inhibitors of protein kinase CK2: an updateBiochemical Journal, 2008
- Constitutively activated FLT3 phosphorylates BAD partially through Pim-1British Journal of Haematology, 2006
- Overexpression of PIM-1 is a potential biomarker in prostate carcinomaJournal of Surgical Oncology, 2005
- Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell LymphomaJournal of Molecular Biology, 2005
- Pim-1 Ligand-bound Structures Reveal the Mechanism of Serine/Threonine Kinase Inhibition by LY294002Online Journal of Public Health Informatics, 2005
- Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 KinaseJournal of Biological Chemistry, 2005
- Pim‐1 kinase promotes inactivation of the pro‐apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper siteFEBS Letters, 2004
- Delineation of prognostic biomarkers in prostate cancerNature, 2001
- Studies on Antidiabetic Agents. X. Synthesis and Biological Activities of Pioglitazone and Related Compounds.CHEMICAL & PHARMACEUTICAL BULLETIN, 1991
- ortho-Directed lithiation of (2-methoxy)ethoxy- and (2-dimethylamino)ethoxy-arenes.CHEMICAL & PHARMACEUTICAL BULLETIN, 1985