Copper(ii)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides
- 1 January 2011
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 47 (13), 3978-3980
- https://doi.org/10.1039/c0cc05557c
Abstract
Copper-catalyzed ortho-benzoxylation of 2-arylpyridine sp2 C–H bonds with acyl chloride is described. Notably, switching the base from t-BuOK to Li2CO3 causes chlorination of the C–H bond to take place.Keywords
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