An International, Randomized, Double-blind, Placebo-Controlled Phase 3 Trial of Intramuscular Alefacept in Patients With Chronic Plaque Psoriasis

Abstract
PSORIASIS IS a chronic, inflammatory, hyperproliferative skin disorder estimated to affect up to 2.5% of the world's population.1 Patients with psoriasis have a range of psychosocial difficulties and stresses commensurate with their physically disfiguring condition.2 This psychosocial aspect of the disease is consistently underestimated and often results in suboptimal care and reduced quality of life.3-5

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