Thalidomide-Related Eosinophilic Pneumonia: A case report and brief literature review
Open Access
- 8 September 2008
- journal article
- Published by Springer Science and Business Media LLC in Cases Journal
- Vol. 1 (1), 143-4
- https://doi.org/10.1186/1757-1626-1-143
Abstract
Thalidomide has regained value in the multimodality treatment of leprosy, multiple myeloma, prostate, ovarian and renal cancer. Complications related to arterial and venous complications are well described. However, pulmonary complications remain relatively uncommon. The most common pulmonary side-effect reported is non-specific dyspnea. We report a patient with multiple myeloma, who developed an eosinophilic pneumonia, shortly after starting thalidomide. She had complete resolution of her symptoms and pulmonary infiltrates on discontinuation of the drug and treatment with corticosteroids. Physicians should be cognizant of this potential complication in patients receiving thalidomide who present with dyspnea and pulmonary infiltrates.Keywords
This publication has 18 references indexed in Scilit:
- Thalidomide-induced reversible interstitial pneumonitis in a patient with recurrent ovarian cancerGynecologic Oncology, 2008
- Arterial and Venous Thrombotic Complications with Thalidomide in Multiple MyelomaArchives of Medical Research, 2008
- Hypersensitivity Pneumonitis-Like Syndrome Associated With the Use of LenalidomideSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 2007
- Thalidomide-induced Organizing PneumoniaSouthern Medical Journal, 2006
- Side Effects and Good Effects from New Chemotherapeutic AgentsJournal of Clinical Oncology, 2005
- Pulmonary hypertension and thalidomide therapy in multiple myeloma.British Journal of Haematology, 2005
- Thalidomide: Current Role in the Treatment of Non-Plasma Cell MalignanciesJournal of Clinical Oncology, 2004
- Primary treatment of multiple myeloma with thalidomide, vincristine, liposomal doxorubicin and dexamethasone(T-VAD doxil): a phase II multicenter studyAnnals of Oncology, 2004
- Reversible pulmonary hypertension and thalidomide therapy for multiple myelomaBritish Journal of Haematology, 2003
- Thalidomide — A Revival StoryThe New England Journal of Medicine, 1999