Transient acute renal failure, hemolysis, and myopathy occurred during an episode of isopropyl alcohol intoxication. Whether these three phenomena represent a direct toxic effect of isopropyl alcohol ingestion remains a matter of conjecture. Only further observations of other cases of isopropyl alcohol poisoning will establish the significance of the features described. Despite the similarities of intoxication with isopropyl alcohol to that with ethyl alcohol, there are certain clinical features which may be of value in differentiating the two.