The Importance of Pets as Reservoirs of Resistant Enterococcus Strains, with Special Reference to Vancomycin
- 28 August 2002
- journal article
- Published by Wiley in Journal of Veterinary Medicine, Series B
- Vol. 49 (6), 278-280
- https://doi.org/10.1046/j.1439-0450.2002.00561.x
Abstract
The purpose of the present study was to determine the prevalence of antibiotic resistance, with special attention to vancomycin, in 104 strains of Enterococcus, which is the sentinel bacterium isolated from dog and cat faeces samples. The phenotypic characterization of the isolates classified them as E. faecium (58%), E. avium (41%) and E. faecalis (1%). Sensitivity testing used the diffusion method according to the recommendations of CASFM (Comite de l'Antibiogramme de la Société Française de Microbiogie), to oxacillin, amoxycillin, amoxycilin + clavulanic acid, ampicillin, piperacillin, cefoperazone, imipenem, enrofloxacin, ciprofloxacin, ofloxacin, nalidixic acid, tetracycline, lincomycin, erythromicin and vancomycin. Minimum inhibitory concentration (MIC) determination by E test revealed a MIC to vancomycin of between 0.5 microg/ml and 3 microg/ml. All the strains were resistant to nalidixic acid, erythromycin, cefoperazone and oxacillin. We detected resistance to amoxycillin + clavulanic acid in 1.9% of isolates, to amoxycillin in 4.8%, to piperacillin in 13.5%, and to ampicillin in 21.2% of strains. A high prevalence of antibiotic resistance to lincomycin, tetracycline, enrofloxacin, ciprofloxacin and ofloxacin was found in 98.1%, 95.2%, 76.9%, 73.1% and 64.4% of strains, respectively. Resistance to vancomycin was not found, which indicates that there is no transmission risk of vancomycin-resistant enterococcal strains to man or transfer of their resistance genes to other bacteria belonging to the endogenous flora of humans.Keywords
This publication has 17 references indexed in Scilit:
- Emergence of Vancomycin-Resistant EnterococciEmerging Infectious Diseases, 2001
- Epidemiology and ecology of enterococci, with special reference to antibiotic resistant strains, in animals, humans and the environment Example of an ongoing project within the European research programmeInternational Journal of Antimicrobial Agents, 2000
- Comité de l'antibiogramme de la société française de microbiologie. Communiqué 1999Medecine Et Maladies Infectieuses, 2000
- Implications of vancomycin-resistant Staphylococcus aureusJournal of Hospital Infection, 1999
- Enterococci and Vancomycin ResistanceClinical Infectious Diseases, 1998
- Multiple-Drug Resistant Enterococci: The Nature of the Problem and an Agenda for the FutureEmerging Infectious Diseases, 1998
- Vancomycin-Resistant Enterococci Outside the Health-Care Setting: Prevalence, Sources, and Public Health ImplicationsEmerging Infectious Diseases, 1997
- Emerging problems with enterococcal infectionsCurrent Opinion in Infectious Diseases, 1996
- Farm animals as a putative reservoir for vancomycin-resistant enterococcal infection in manJournal of Antimicrobial Chemotherapy, 1994
- Cowan and Steel's Manual for the Identification of Medical BacteriaPublished by Cambridge University Press (CUP) ,1993