Upper Airway Resistance Syndrome
- 1 August 2000
- journal article
- Published by American Thoracic Society in American Journal of Respiratory and Critical Care Medicine
- Vol. 162 (2), 406-411
- https://doi.org/10.1164/ajrccm.162.2.9901026
Abstract
Upper airway resistance syndrome (UARS) is defined by excessive daytime sleepiness and tiredness, and is associated with increased breathing effort. Its polygraphic features involve progressive increases in esophageal pressure (Pes), terminated by arousal (AR) as defined by the American Sleep Disorders Association (ASDA). With the arousal there is an abrupt decrease in Pes, called Pes reversal. However, Pes reversal can be seen without the presence of an AR. We performed spectral analysis on electroencephalographic data from a central lead for both AR and nonarousal (N-AR) events obtained from 15 UARS patients (eight men and seven women). Delta band activity was increased before and surrounding Pes reversal regardless of the presence or absence of AR. In the period after Pes reversal, alpha, sigma, and beta activity showed a greater increase in AR events than in N-AR events. The Pes measures were identical leading up to the point of reversal, but showed a longer-lasting and significantly greater decrease in respiratory effort after an AR. The data indicate that substantial electroencephalographic changes can be identified in association with Pes events, even when ARs cannot be detected according to standard criteria; however, visually identifiable electroencephalographic arousals clearly have a greater impact on ongoing inspiratory effort.Keywords
This publication has 19 references indexed in Scilit:
- Study on Ge/Si ratio, silicidation, and strain relaxation of high temperature sputtered Co/Si1−xGex structuresJournal of Applied Physics, 2000
- The N550 component of the evoked K‐complex: A modality non‐specific response?Journal of Sleep Research, 1999
- Respiratory‐related evoked potentials during the transition from alpha to theta EEG activity in Stage 1 NREM sleepJournal of Sleep Research, 1999
- Multichannel EEG analysis of respiratory evoked-potential components during wakefulness and NREM sleep.Journal of Applied Physiology, 1998
- Activity of respiratory pump and upper airway muscles during sleep onsetJournal of Applied Physiology, 1998
- Gender differences in airway resistance during sleep.Journal of Applied Physiology, 1997
- The effect of nonvisible sleep fragmentation on daytime function.American Journal of Respiratory and Critical Care Medicine, 1997
- Arousal responses from apneic events during non-rapid-eye-movement sleep.American Journal of Respiratory and Critical Care Medicine, 1995
- A Cause of Excessive Daytime SleepinessChest, 1993
- Determinants of Daytime Sleepiness in Obstructive Sleep ApneaChest, 1988