Photoredox-Induced Three-Component Oxy-, Amino-, and Carbotrifluoromethylation of Enecarbamates
- 12 February 2014
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 16 (4), 1240-1243
- https://doi.org/10.1021/ol500374e
Abstract
A photoredox-catalzyed trifluoromethylation of enecarbamates process is reported. This pathway uses Togni’s reagent as the CF3 source and follows a radical/cationic pathway. Under the optimized conditions using [Ru(bpy)3(PF6)2] as the photocatalyst, a wide range of substituted enecarbamates can readily be difunctionalized by means of various O, N, and C nucleophiles.Keywords
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