DNA Sequence of the mini-insertion IS2–6 and its relation to the sequence of IS2
- 1 October 1978
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 275 (5681), 611-617
- https://doi.org/10.1038/275611a0
Abstract
In polar orientation IS2 abolishes galactose operon expression. Operon activity is restored by a 108 base pair mini-insertion within IS2 called IS2–6. The DNA sequences of the gal operon -IS2 junction, the parental IS2 region undergoing sequence rearrangements and IS2–6 itself are reported. IS2–6 is composed of sequence intervals present in both strands of IS2.This publication has 10 references indexed in Scilit:
- Insertion sequence IS2 associated with int-constitutive mutants of bacteriophage lambdaGene, 1977
- A new method for sequencing DNA.Proceedings of the National Academy of Sciences, 1977
- Nucleotide sequence of the operator-promoter region of the galactose operon of Escherichia coli.Proceedings of the National Academy of Sciences of the United States of America, 1977
- Isolation of the mini insertions IS6 and IS7 of E. coliMolecular Genetics and Genomics, 1977
- A map of the sites on bacteriophage PM2 DNA for the restriction endonucleases HindIII and HpaIIJournal of Molecular Biology, 1976
- Mapping of Cleavage Sites for Restriction Endonucleases in λdv PlasmidsEuropean Journal of Biochemistry, 1975
- A freeze-squeeze method for recovering long DNA from agarose gelsAnalytical Biochemistry, 1975
- Localization of translation initiation in the message forBiochemical and Biophysical Research Communications, 1974
- IS2, a genetic element for turn-off and turn-on of gene activity in E. coliMolecular Genetics and Genomics, 1974
- Multiple copies of the insertion-DNA sequences IS1 and IS2 in the chromosome of E. coli K-12Molecular Genetics and Genomics, 1973