Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-β1 in Renal Tubular Epithelial Cells
- 1 August 2009
- journal article
- research article
- Published by Elsevier BV in The American Journal of Pathology
- Vol. 175 (2), 580-591
- https://doi.org/10.2353/ajpath.2009.080983
Abstract
No abstract availableThis publication has 59 references indexed in Scilit:
- NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherinThe EMBO Journal, 2008
- Twisted epithelial–mesenchymal transition blocks senescenceNature, 2008
- Protein kinase B/Akt activity is involved in renal TGF-β1-driven epithelial-mesenchymal transition in vitro and in vivoAmerican Journal of Physiology-Renal Physiology, 2008
- Tubular Epithelial Cell Dedifferentiation Is Driven by the Helix-Loop-Helix Transcriptional Inhibitor Id1Journal of the American Society of Nephrology, 2007
- Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidneyThe EMBO Journal, 2006
- Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrixProceedings of the National Academy of Sciences of the United States of America, 2006
- Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapyNature Reviews Cancer, 2006
- Plasmin is not protective in experimental renal interstitial fibrosis1Kidney International, 2004
- Integrin β1 Signaling Is Necessary for Transforming Growth Factor-β Activation of p38MAPK and Epithelial PlasticityPublished by Elsevier BV ,2001
- The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cellsNature, 2000