Beyond drug use: a systematic consideration of other outcomes in evaluations of treatments for substance use disorders
- 7 October 2011
- Vol. 107 (4), 709-718
- https://doi.org/10.1111/j.1360-0443.2011.03581.x
Abstract
Across the addictions field, the primary outcome in treatment research has been reduction in drug consumption. A comprehensive view of the impact of substance use disorders on human functioning suggests that effective treatments should address the many consequences and features of addiction beyond drug use, a recommendation forwarded by multiple expert panels and review papers. Despite recurring proposals, and a compelling general rationale for moving beyond drug use as the sole standard for evaluating addiction treatment, the field has yet to adopt any core set of ‘other’ measures that are routinely incorporated into treatment research. Among the many reasons for the limited impact of previous proposals has been the absence of a clear set of guidelines for selecting candidate outcomes. This paper is the result of the deliberations of a panel of substance abuse treatment and research experts convened by the National Institute on Drug Abuse to discuss appropriate outcome measures for clinical trials of substance abuse treatments. This paper provides an overview of previous recommendations and outlines specific guidelines for consideration of candidate outcomes. A list of outcomes meeting those guidelines is described and illustrated in detail with two outcomes: craving and quality of life. The paper concludes with specific recommendations for moving beyond the outcome listing offered in this paper to promote the programmatic incorporation of these outcomes into treatment research.Keywords
This publication has 113 references indexed in Scilit:
- Personal network correlates of alcohol, cigarette, and marijuana use among homeless youthDrug and Alcohol Dependence, 2010
- Neurocircuitry of AddictionNeuropsychopharmacology, 2009
- Don't Wanna Go Through That Madness No More: Quality of Life Satisfaction as Predictor of Sustained Remission from Illicit Drug MisuseSubstance Use & Misuse, 2009
- Neurobiological mechanisms for opponent motivational processes in addictionPhilosophical Transactions B, 2008
- Self-efficacy for cocaine abstinence: Pretreatment correlates and relationship to outcomesAddictive Behaviors, 2008
- Psychosocial functioning and cocaine use during treatment: Strength of relationship depends on type of urine-testing methodDrug and Alcohol Dependence, 2007
- Theory-based processes that promote the remission of substance use disordersClinical Psychology Review, 2007
- Developing adaptive treatment strategies in substance abuse researchDrug and Alcohol Dependence, 2007
- The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in OncologyJNCI Journal of the National Cancer Institute, 1993
- The MOS 36-ltem Short-Form Health Survey (SF-36)Medical Care, 1992