We evaluated the mortality and morbidity of acute cerebral infarction as related to modifiable factors: glucose level, temperature, hematocrit, hemoglobin and platelet count. We studied 177 patients with acute cerebral infarction in the territory of the middle cerebral artery, admitted within 24 h of stroke onset. Blood was drawn on admission and temperature was recorded every 2 h, selecting the highest during the 1st day. Patient follow-up lasted 6 months. Barthel Index and Neurological Score of patients were evaluated at admission and on days 1, 4, 7, 14, 21 and at 3 and 6 months. A Glasgow Scale was administered at 6 months. Forty-five of 177 patients died within this period. These patients reached a temperature of 38.3 ± 0.76 °C, while temperature in those surviving was 36.9 ± 0.46°C ( p